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Intestinal Epithelial Axin1 Deficiency Protects Against Colitis via Altered Gut Microbiota

Shari Garrett,Yongguo Zhang,Yinglin Xia,Jun Sun,

Engineering doi: 10.1016/j.eng.2023.06.007

Abstract: signaling, but little is known regarding its role in regulating host–microbial interactions in health and diseaseAxin1 expression was analyzed in human inflammatory bowel disease datasets.We found increased Axin1 expression in the colonic epithelium of human inflammatory bowel disease (IBDmechanistic studies using specific Axin1 mutations elucidating how Axin1 modulates the microbiome and host inflammatory

Keywords： Axin1     Bacteria     Microbiome inflammation     Inflammatory bowel disease     Immunity     Microbiome     Paneth cells     Akkermansia    

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A ruptured recurrent small bowel gastrointestinal stromal tumour causing hemoperitoneum

Eric C.H. Lai,Kam Man Chung,Stephanie H.Y. Lau,Wan Yee Lau

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 108-111 doi: 10.1007/s11684-014-0344-0

Abstract: intra-abdominal recurrence from a previously resected gastrointestinal stromal tumour (GIST) of the small bowelDespite the presence of residual disease, the patient was well clinically 8 months after the operationIn our patient, disease progression after second line targeted therapy and the absence of alternative

Keywords： gastrointestinal stromal tumour     hemoperitoneum     small bowel GIST     small bowel neoplasm     imatinib    

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Effect of levonorgestrel intrauterine system on IGF-1 and the dependablity study of prevention pelvic inflammatorydisease

Wu Xiaojie,Liu Xia,Tao Yueping,Wang Jie

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 4-7

Abstract: disease.Patients were followed up for 2Syears to analyse the effluence of pelvic inflammatory disease.Followed up for 2 years, 14 cases has pelvic inflammatory disease in study group,39 cases has pelvicinflammatory disease in control group,there was a significant differences.Conclusions:It may be the mainSmechanism of Prevention pelvic inflammatory disease and inhibition endometrium

Keywords： levonorgestrel     Intrauterine system insulin-like growth factor-1     pelvic inflammatory disease    

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Severe adhesive small bowel obstruction

Salomone Di Saverio, Fausto Catena, Michael D. Kelly, Gregorio Tugnoli, Luca Ansaloni

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 436-439 doi: 10.1007/s11684-012-0221-7

Abstract:

Adhesive small bowel obstruction is a frequent cause of hospital admission.may have diagnostic and therapeutic value and avoid challenging demanding surgical operations, but if bowelA 58-year-old patient was operated for extensive adhesive small bowel obstruction after having had twoFor patients admitted several times for adhesive small bowel obstruction, the relative risk of recurringSeveral strategies for non-operative conservative management of adhesive small bowel obstruction have

Keywords： post-operative intraperitoneal adhesions     adhesive small bowel obstruction     adhesiolysis     antiadhesion treatments    

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ADT-OH improves intestinal barrier function and remodels the gut microbiota in DSS-induced colitis

Frontiers of Medicine   Pages 972-992 doi: 10.1007/s11684-023-0990-1

Abstract: Owing to the increasing incidence and prevalence of inflammatory bowel disease (IBD) worldwide, effectiveTo date, H2S-releasing agents are viewed as potential anti-inflammatory drugs.Here, we reported its anti-inflammatory effects on dextran sodium sulfate (DSS)-induced acute (7 days

Keywords： inflammatory bowel disease     ADT-OH     intestinal permeability     gut microbiota    

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Improved dissolution and anti-inflammatory effect of ibuprofen by solid dispersion

Liyuan Chen, Qifeng Dang, Chengsheng Liu, Jun Chen, Lei Song, Xiguang Chen

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 195-203 doi: 10.1007/s11684-012-0189-3

Abstract:

The purpose of this study was to improve the dissolution rate and anti-inflammatory effect of ibuprofenThe anti-inflammatory effect of SDBT was evaluated using the mouse ear edema test with xylene.SDBT displayed more significant anti-inflammatory effects than CT.The dissolution rate and anti-inflammatory effect of ibuprofen were significantly enhanced by the ibuprofen-urea

Keywords： ibuprofen     solid dispersion     physical mixture     dissolution     anti-inflammatory effect    

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Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 239-248 doi: 10.1007/s11684-018-0617-0

Abstract: In fact, several studies indicated that acute and chronic allograft rejection in small bowel transplantation

Keywords： gut microbiota     small bowel transplantation     acute rejection     chronic rejection     mucosal immunity     biomarker    

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Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 139-145 doi: 10.1007/s11684-015-0377-z

Abstract: view is supported by a large body of literature, it has been challenged by growing evidence that pro-inflammatoryarticle, interleukin 15 (IL-15) is used as a new example to explain the beneficial effects of the pro-inflammatoryIn summary, evidence from human and rodents supports that the pro-inflammatory cytokine IL-15 may enhance

Keywords： inflammation     obesity     cytokine     energy expenditure     insulin resistance    

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Research about bacteriology on intrauterine device

Zhang Xianghui,Qu Wenwen,Huang Wei,Fang Jie,Wu Fanzi,Zhou Xinxuan

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 21-27

Abstract: contraception，while concerns still exist as to whether the use of IUD increases the risk of pelvic inflammatorydisease（PID）.

Keywords： intrauterine device     pelvic inflammatory disease     bacterial biofilm     scanning electron microscopy    

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Bioactive hyaluronic acid fragments inhibit lipopolysaccharide-induced inflammatory responses via the

Na You, Sasa Chu, Binggang Cai, Youfang Gao, Mizhou Hui, Jin Zhu, Maorong Wang

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 292-301 doi: 10.1007/s11684-020-0806-5

Abstract: However, the role of LMW-HA in inflammatory response is controversial.aimed to investigate the effect of bioactive hyaluronan (B-HA) on lipopolysaccharide (LPS)-induced inflammatorycytokine IL-10 in LPS-induced inflammatory responses in THP-1-derived macrophages and .In conclusion, our results demonstrated that the B-HA attenuated the LPS-stimulated inflammatory responseB-HA could be a potential anti-inflammatory drug in the treatment of inflammatory disease.

Keywords： bioactive hyaluronan     lipopolysaccharide     inflammatory cytokines     TLR4     human macrophages    

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Non-genetic mechanisms of diabetic nephropathy

Qiuxia Han, Hanyu Zhu, Xiangmei Chen, Zhangsuo Liu

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 319-332 doi: 10.1007/s11684-017-0569-9

Abstract: DN has become the leading cause of end-stage renal disease.However, this disease is multifactorial, and its mechanism is poorly understood due to the complex pathogenesis

Keywords： diabetic nephropathy     immune inflammatory response     epithelial–mesenchymal transition     apoptosis     mitochondrial    

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et’s disease in a Chinese population

Shengping Hou, Aize Kijlstra, Peizeng Yang

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 354-359 doi: 10.1007/s11684-012-0234-2

Abstract: et’s disease is defined as a multisystemic inflammatory disease.et’s disease. To explore the genetic factors for Beh?et’s disease, our group investigated the association of Beh?et’s disease with multiple immune response genes and has identified multiple Beh?et’s disease-related immunoregulatory pathways in the Chinese Han population.

Keywords： et’s disease     SNPs     immune gene     genetic study    

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Metformin and metabolic diseases: a focus on hepatic aspects

Juan Zheng,Shih-Lung Woo,Xiang Hu,Rachel Botchlett,Lulu Chen,Yuqing Huo,Chaodong Wu

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 173-186 doi: 10.1007/s11684-015-0384-0

Abstract: beneficial effects of metformin implicate a role for metformin in managing non-alcoholic fatty liver disease

Keywords： metformin     diabetes     hepatic steatosis     inflammatory response     insulin resistance    

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Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 425-432 doi: 10.1007/s11684-013-0295-x

Abstract:

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortalityCertain heterogeneities are found in terms of clinical manifestations, physiology, imaging findings, and inflammatory

Keywords： chronic obstructive pulmonary disease     heterogeneity     phenotype     genotype     prediction    

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Acupuncture for the management of dry eye disease

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 975-983 doi: 10.1007/s11684-022-0923-4

Abstract: The effectiveness of using acupuncture for dry eye disease (DED) is controversial.outcomes of interests were (1) to evaluate the efficacy of acupuncture in improving the ocular surface disease

Keywords： dry eye disease     xerophthalmus     acupuncture    

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Title Author Date Type Operation

Intestinal Epithelial Axin1 Deficiency Protects Against Colitis via Altered Gut Microbiota

Shari Garrett,Yongguo Zhang,Yinglin Xia,Jun Sun,

Journal Article

A ruptured recurrent small bowel gastrointestinal stromal tumour causing hemoperitoneum

Eric C.H. Lai,Kam Man Chung,Stephanie H.Y. Lau,Wan Yee Lau

Journal Article

Effect of levonorgestrel intrauterine system on IGF-1 and the dependablity study of prevention pelvic inflammatorydisease

Wu Xiaojie,Liu Xia,Tao Yueping,Wang Jie

Journal Article

Severe adhesive small bowel obstruction

Salomone Di Saverio, Fausto Catena, Michael D. Kelly, Gregorio Tugnoli, Luca Ansaloni

Journal Article

ADT-OH improves intestinal barrier function and remodels the gut microbiota in DSS-induced colitis

Journal Article

Improved dissolution and anti-inflammatory effect of ibuprofen by solid dispersion

Liyuan Chen, Qifeng Dang, Chengsheng Liu, Jun Chen, Lei Song, Xiguang Chen

Journal Article

Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Journal Article

Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Journal Article

Research about bacteriology on intrauterine device

Zhang Xianghui,Qu Wenwen,Huang Wei,Fang Jie,Wu Fanzi,Zhou Xinxuan

Journal Article

Bioactive hyaluronic acid fragments inhibit lipopolysaccharide-induced inflammatory responses via the

Na You, Sasa Chu, Binggang Cai, Youfang Gao, Mizhou Hui, Jin Zhu, Maorong Wang

Journal Article

Non-genetic mechanisms of diabetic nephropathy

Qiuxia Han, Hanyu Zhu, Xiangmei Chen, Zhangsuo Liu

Journal Article

et’s disease in a Chinese population

Shengping Hou, Aize Kijlstra, Peizeng Yang

Journal Article

Metformin and metabolic diseases: a focus on hepatic aspects

Juan Zheng,Shih-Lung Woo,Xiang Hu,Rachel Botchlett,Lulu Chen,Yuqing Huo,Chaodong Wu

Journal Article

Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Journal Article

Acupuncture for the management of dry eye disease

Journal Article